The deubiquitinating enzyme USP25 restricts ubiquitination of the adaptors TRAF5 and TRAF6 and signaling via interleukin 17 and thus joins several ubiquitin-modifying enzymes already known to regulate this biomedically important pathway.
This is a preview of subscription content, access via your institution
Relevant articles
Open Access articles citing this article.
-
Knockout of interleukin-17A protects against sepsis-associated acute kidney injury
Annals of Intensive Care Open Access 22 June 2016
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Gaffen, S.L. Curr. Opin. Immunol. 23, 613–619 (2011).
Spits, H. & Di Santo, J.P. Nat. Immunol. 12, 21–27 (2011).
Zhong, B. et al. Nat. Immunol. 12, 1110–1117 (2012).
Zepp, J.A. et al. J. Immunol. 189, 33–37 (2012).
Sun, D. et al. Nat. Immunol. 12, 853–860 (2011).
Bulek, K. et al. Nat. Immunol. 12, 844–852 (2011).
Chen, Z.J. Immunol. Rev. 246, 95–106 (2012).
Wiener, R., Zhang, X., Wang, T. & Wolberger, C. Nature 483, 618–622 (2012).
Shembade, N., Ma, A. & Harhaj, E. Science 327, 1135–1139 (2010).
Meulmeester, E., Kunze, M., Hsiao, H.H., Urlaub, H. & Melchior, F. Mol. Cell 30, 610–619 (2008).
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Competing interests
The author declares no competing financial interests.
Rights and permissions
About this article
Cite this article
Ma, A. The ubiquitous nature of IL-17. Nat Immunol 13, 1034–1035 (2012). https://doi.org/10.1038/ni.2448
Published:
Issue Date:
DOI: https://doi.org/10.1038/ni.2448
This article is cited by
-
Knockout of interleukin-17A protects against sepsis-associated acute kidney injury
Annals of Intensive Care (2016)