The axis of lymphotoxin and its receptor LTβR influences the composition of the host gut microbiome, leading to excessive weight gain in hosts fed a high-fat diet.
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Ubeda, C., Pamer, E. Securing the border: lymphotoxin, IL-23 and IL-22 keep out the bad guys and 'fatten' the homeland. Nat Immunol 13, 940–941 (2012). https://doi.org/10.1038/ni.2425
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DOI: https://doi.org/10.1038/ni.2425
