Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Provocative exhibits at the Seventeen Gallery

Two studies identify a tissue-autonomous innate immune mechanism whereby infection provokes epithelial cells to produce IL-17C that engages an epithelial receptor composed of IL-17RA and IL-17RE chains, which promotes host defense and immune activation.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: A revised view of the IL-17 portfolio.

References

  1. Rutherford, J. in Identity, Community, Culture, Difference (ed. Rutherford, J.) 211 (Lawrence and Wishart, London, 1990).

    Google Scholar 

  2. Ramirez-Carozzi, V. et al. Nat. Immunol. 12, 1159–1166 (2011).

    Article  Google Scholar 

  3. Song, X. et al. Nat. Immunol. 12, 1151–1158 (2011).

    Article  CAS  Google Scholar 

  4. Chang, S.H. et al. Immunity published online, doi:10.1016/j.immuni.2011.09.010 (6 October 2011).

  5. Fossier, F. et al. J. Exp. Med. 183, 2593–2603 (1996).

    Article  Google Scholar 

  6. Harrington, L.E., Mangan, P.R. & Weaver, C.T. Curr. Opin. Immunol. 18, 349–356 (2006).

    Article  CAS  Google Scholar 

  7. Ribot, J.C. et al. Nat. Immunol. 10, 427–436 (2009).

    Article  CAS  Google Scholar 

  8. Sutton, C.E. et al. Immunity 31, 331–341 (2009).

    Article  CAS  Google Scholar 

  9. Shibata, K., Yamada, H., Hara, H., Kishihara, K. & Yoshikai, Y. J. Immunol. 178, 4466–4472 (2007).

    Article  CAS  Google Scholar 

  10. Puel, A. et al. Science 332, 65–68 (2011).

    Article  CAS  Google Scholar 

  11. Duerr, R.H. et al. Science 314, 1461–1463 (2006).

    Article  CAS  Google Scholar 

  12. Swamy, M., Jamora, C., Havran, W. & Hayday, A. Nat. Immunol. 11, 656–665 (2010).

    Article  CAS  Google Scholar 

  13. Zheng, Y. et al. Nat. Med. 14, 282–289 (2008).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Adrian Hayday.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Swamy, M., Hayday, A. Provocative exhibits at the Seventeen Gallery. Nat Immunol 12, 1131–1133 (2011). https://doi.org/10.1038/ni.2164

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ni.2164

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing