NUR who? An orphan transcription factor holds promise for monomaniacs

The generation of Ly6C patrolling monocytes requires the transcription factor NR4A1 (Nur77). This finding provides insight into the development and function of these blood-resident cells.

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Figure 1: Monocytes and their potential derivatives.

Katie Vicari

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Correspondence to Michael D Gunn.

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The authors declare no competing financial interests.

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Cain, D., Gunn, M. NUR who? An orphan transcription factor holds promise for monomaniacs. Nat Immunol 12, 727–729 (2011). https://doi.org/10.1038/ni.2074

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