Abstract
The endodermal epithelium of vertebrates generates many types of enteroendocrine cells, including the insulin- and glucagon-secreting cells of the islets of Langerhans. Two studies disclose that Notch signalling controls which cells differentiate as enteroendocrine cells—a finding with implications for therapeutic strategy.
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Skipper, M., Lewis, J. Getting to the guts of enteroendocrine differentiation. Nat Genet 24, 3–4 (2000). https://doi.org/10.1038/71653
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DOI: https://doi.org/10.1038/71653
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