Department of Epidemiology and Biostatistics, School of Public Health, Imperial College of London, London, UK
John C Chambers, Weihua Zhang, Marjo-Riitta Jarvelin & Paul Elliott
Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK
John C Chambers, Weihua Zhang, Joban S Sehmi, Ranil de Silva & Jaspal S Kooner
Department of Nephrology and Transplantation, King's College London, UK
Graham M Lord, Maria Hernandez-Fuentes & Esperanza Perucha
Medical Research Council (MRC) Centre for Transplantation, King's College London, UK
Graham M Lord, Maria Hernandez-Fuentes & Esperanza Perucha
National Institute for Health Research (NIHR) Comprehensive Biomedical Research Centre, Guy's and St. Thomas' NHS Foundation Trust and King's College London, London, UK
Graham M Lord, Maria Hernandez-Fuentes & Esperanza Perucha
University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Pim van der Harst, Stephan J L Bakker, Henk J G Bilo & Gerjan Navis
MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK
Debbie A Lawlor & George Davey Smith
National Heart and Lung Institute, Hammersmith Hospital Campus, Imperial College London, London, UK
Joban S Sehmi, Ranil de Silva, James Scott & Jaspal S Kooner
Division of Medicine, University College London, London, UK
Daniel P Gale & Patrick H Maxwell
Structural Bioinformatics Group, Imperial College London, London, UK
Mark N Wass & Michael J E Sternberg
Twin Research and Genetic Epidemiology Department, King's College London, St. Thomas' Hospital Campus, London, UK
Kourosh R Ahmadi, Ioana Cotlarciuc, Nicole Soranzo & Timothy D Spector
Department of Medical Genetics, University of Lausanne, Lausanne, Switzerland
Jacqui Beckmann
University Institute of Social and Preventive Medicine, Centre Hospitalier Universitaire Vaudois (CHUV), Lausanne, Switzerland
Murielle Bochud
Clinical Pharmacology Unit, University of Cambridge, Addenbrookes Hospital, Cambridge, UK
Morris J Brown
Clinical Pharmacology and The Genome Centre, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, London, UK
Mark J Caulfield & Patricia B Munroe
Glasgow Cardiovascular Research Centre, University of Glasgow, Glasgow, UK
John M C Connell & Anna Dominiczak
Department of Histopathology, Imperial College, Hammersmith Hospital, London, UK
H Terence Cook
Department of Gastroenterology and Hepatology, Imperial College London, London, UK
Guohong Deng
Division of Nephrology, Université Catholique de Louvain Medical School, Brussels, Belgium
Olivier Devuyst & Céline Maréchal
Isala Clinics, Zwolle, The Netherlands
Lambert D Dikkeschei
Center for Renal Diseases, Zvezdara University Medical Center, Belgrade, Serbia
Nada Dimkovic
South West Thames Institute for Renal Research, Epsom and St. Helier University Hospitals NHS Trust, Carshalton, UK
Mark Dockrell & Marta Lapsley
London School of Hygiene and Tropical Medicine, London, UK
Shah Ebrahim
Department of Human Genetics, Rheinisch-Westfaelische Technische Hochschule University Hospital Aachen, Aachen, Germany
Thomas Eggermann & Klaus Zerres
Cardiovascular Medicine, University of Oxford, Wellcome Trust Centre for Human Genetics, Oxford, UK
Martin Farrall
National Institute of Aging, Clinical Research Branch–Longitudinal Studies Section, Baltimore, Maryland, USA
Luigi Ferrucci & Toshiko Tanaka
Department of Nephrology and Clinical Immunology, RWTH University Hospital Aachen, Aachen, Germany
Jurgen Floege & Georg Schlieper
MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK
Nita G Forouhi, Ruth J F Loos, Jian'an Luan & Nicholas J Wareham
Department of Internal Medicine, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Ron T Gansevoort & Marc A J Seelen
Center for Statistical Genetics, University of Michigan, Ann Arbor, Michigan, USA
Xijin Han, Yun Li & Goncalo R Abecasis
Department of Clinical Sciences, Lund University, Malmö, Sweden
Bo Hedblad, Olle Melander & Marketa Sjögren
Department of Nephrology, University Medical Center Groningen, Groningen, The Netherlands
Jaap J Homan van der Heide
Department of Transplantation Immunology, University Medical Center Groningen, Groningen, The Netherlands
Bouke G Hepkema
Centre of Epidemiology for Child Health, University College London Institute of Child Health, London, UK
Elina Hypponen
Department of Medical Genetics, University of Lausanne and the Swiss Institute of Bioinformatics, Lausanne, Switzerland
Toby Johnson
Langerhans Medical Research Group, Zwolle, The Netherlands
Paul E de Jong & Nanne Kleefstra
Department of Epidemiology, Unit of Genetic Epidemiology and Bioinformatics, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Vasiliki Lagou & Harold Snieder
Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Karin Luttropp & Louise Nordfors
Division of Nephrology, University of Maryland School of Medicine, Baltimore, Maryland, USA
Afshin Parsa
Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK
Leena Peltonen
Institute for Molecular Medicine Finland (FIMM), Nordic European Molecular Biology Laboratory (EMBL) Partnership for Molecular Medicine, Biomedicum Helsinki 2U and University of Helsinki, Helsinki, Finland
Leena Peltonen
National Institute for Health and Welfare, Helsinki, Finland
Leena Peltonen, Anneli Pouta & Marjo-Riitta Jarvelin
Department of Psychiatry, Institute for Research in Extramural Medicine (EMGO), Neuroscience Campus, Vrije Universiteit (VU) Medical Center, Amsterdam, The Netherlands
Brenda W Penninx & Johannes H Smit
Department of Psychiatry, Leiden University Medical Center, Leiden, The Netherlands
Brenda W Penninx & Johannes H Smit
Department of Psychiatry, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands
Brenda W Penninx & Johannes H Smit
Institute of Health Sciences, University of Oulu, Oulu, Finland
Anneli Pouta & Marjo-Riitta Jarvelin
Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
Inga Prokopenko & Mark I McCarthy
Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford, UK
Inga Prokopenko & Mark I McCarthy
Oxford NIHR Biomedical Research Centre, Oxford, UK
Inga Prokopenko & Mark I McCarthy
University of Southampton, Southampton, UK
Paul J Roderick
Department of Clinical Chemistry, Institute of Clinical Medicine, University of Oulu, Oulu, Finland
Aimo Ruokonen
Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK
Nilesh J Samani
Istituto di Neurogenetica e Neurofarmacologia, Consiglio Nazionale delle Ricerche, Cagliari, Italy
Serena Sanna & Manuela Uda
Department of Molecular Medicine and Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm, Sweden
Martin Schalling
Laboratory of Genetics, US National Institutes of Health Biomedical Research Center, National Institute on Aging, Baltimore, Maryland, USA
David Schlessinger
Division of Endocrinology, Diabetes and Nutrition, University of Maryland School of Medicine, Baltimore, Maryland, USA
Alan R Shuldiner
Division of Renal Medicine K56, Karolinska University Hospital at Huddinge, Stockholm, Sweden
Peter Stenvinkel
Chemical Pathology, Guy's and St Thomas' Hospitals Trust, London, UK
Ramasamyiyer Swaminathan
General Practice 't Veen, Hattem, The Netherlands
Lielith J Ubink-Veltmaat
Department of Internal Medicine, University Hospital Center, University of Lausanne, Lausanne, Switzerland
Peter Vollenweider & Gerard Waeber
Cambridge Institute for Medical Research, Addenbrooke's Hospital, Hills Road, Cambridge, UK
Chris Wallace
Medical Genetics, Clinical Pharmacology and Discovery Medicine, GlaxoSmithKline, King of Prussia, Pennsylvania, USA
Dawn Waterworth & Vincent Mooser
Biocenter Oulu, University of Oulu, Oulu, Finland
Marjo-Riitta Jarvelin
Division of Medicine, Renal Section, Hammersmith Hospital Campus, Imperial College London, London, UK
Liz Lightstone
Department of Epidemiology and Public Health, MRC-HPA Centre for Environment and Health, Imperial College of London, London, UK
Paul Elliott
J.C.C., P.E., L.L., J.S., G.N. and J.S.K. designed the study. J.C.C., W.Z., D.A.L. and P.v.d.H. led the data analysis. J.C.C., P.E., L.L., J.S., G.N. and J.S.K. wrote the manuscript, with contributions from all the authors.