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Ironing out hereditary overload

Researchers studying the structure of a protein that is mutated in one of the commonest hereditary diseases have shed light on how our bodies pump iron. Christopher Surridge explains.

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References

  1. Bennett,M. J., Lebrón, J. A. & Bjorkman, P. J. Crystal structure of the hereditary haemochromatosis protein HFE complexed with transferrin receptor. Nature 403, 46 2000.

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Surridge, C. Ironing out hereditary overload. Nature (2000). https://doi.org/10.1038/news000106-14

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