Mouse-brain study shows protein plaques to be a cause of the problem.
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References
Meyer-Luehmann, M. et al. Nature 451, 720?724 (2008).
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Ledford, H. Window opened on Alzheimer's conundrum. Nature (2008). https://doi.org/10.1038/news.2008.551
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DOI: https://doi.org/10.1038/news.2008.551