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Structure and Subunit Interaction of Haemoglobin M Milwaukee

Abstract

In haemoglobin M Milwaukee, substitution of a glutamic acid for a valine in the haem pocket of the β chains leads to a link between the γ carboxyl group and the ferric iron. Interaction between ferrous and ferric haems is observed.

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PERUTZ, M., PULSINELLI, P. & RANNEY, H. Structure and Subunit Interaction of Haemoglobin M Milwaukee. Nature New Biology 237, 259–263 (1972). https://doi.org/10.1038/newbio237259a0

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