Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Case Study
  • Published:

Emphysematous pyelonephritis

Abstract

Background A 54-year-old nondiabetic male presented with high fever, vague lower abdominal pain and leakage of urine around his long-standing suprapubic catheter. Examination revealed pyrexia and tenderness in the right renal angle. White cell count was 22.8 × 109/l. Plain abdominal X-ray showed calculi in the right kidney, ureter and bladder. Intravenous pyelogram showed gas confined to the right upper renal pelvis and perinephric space.

Investigations Urine and blood cultures, plain abdominal X-ray, intravenous pyelogram, abdominal ultrasound, MAG3 renogram and histopathology.

Diagnosis Emphysematous pyelonephritis: class 2 or type 1. Escherichia coli was isolated from urine obtained by endoscopic drainage.

Management Endoscopic drainage of pus and simple nephrectomy.

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Intravenous pyleogram showing gas confined to the right upper renal pelvis and perirenal space.
Figure 2: Ultrasound scan of the right kidney, showing gross distension and echogenic debris (arrows) within the collecting system.

References

  1. Schaeffer AJ (2002) Infections of the Urinary Tract. In Campell's urology, edn 8, 556–558 (Eds Walsh PC et al.) Philadelphia, London: Saunders

  2. McHugh TP et al. (1998) Bilateral emphysematous pyelonephritis. Am J Emerg Med 16: 166–169

    Article  CAS  Google Scholar 

  3. Wan YL et al. (1996) Acute gas-producing bacterial renal infection: correlation between imaging findings and clinical outcome. Radiology 198: 433–438

    Article  CAS  Google Scholar 

  4. Huang JJ and Tseng CC (2000) Emphysematous pyelonephritis: clinicoradiological classification, management, prognosis, and pathogenesis. Arch Intern Med 160: 797–805

    Article  CAS  Google Scholar 

  5. Flores G et al. (2002) Acute bilateral emphysematous pyelonephritis successfully managed by medical therapy alone: a case report and review of the literature. BMC Nephrol 3: 4

    Article  Google Scholar 

  6. Evanoff GV et al. (1987) Spectrum of gas within the kidney. Emphysematous pyelonephritis and emphysematous pyelitis. Am J Med 83: 149–154

    Article  CAS  Google Scholar 

  7. Chen MT et al. (1997) Percutaneous drainage in the treatment of emphysematous pyelonephritis: 10-year experience. J Urol 157: 1569–1573

    Article  CAS  Google Scholar 

  8. Huang JJ et al. (1991) Mixed acid fermentation of glucose as a mechanism of emphysematous urinary tract infection. J Urol 146: 148–151

    Article  CAS  Google Scholar 

  9. Michaeli J et al. (1984) Emphysematous pyelonephritis. J Urol 131: 203–208

    Article  CAS  Google Scholar 

  10. Chao R et al. (1993) Fate of upper urinary tracts in patients with indwelling catheters after spinal cord injury. Urology 42: 259–262

    Article  CAS  Google Scholar 

  11. Patterson JE and Andriole VT (1997) Bacterial urinary tract infections in diabetics. Infect Dis Clin North Am 11: 735–750

    Article  CAS  Google Scholar 

  12. Jong IC et al. (1998) Emphysematous pyelonephritis in two diabetic patients with complete uterine prolapse and cystocele. Nephrol Dial Transplant 13: 3214–3217

    Article  CAS  Google Scholar 

  13. Turney JH (2000) Renal conservation for gas-forming infections. Lancet 355: 770–771

    Article  CAS  Google Scholar 

  14. Best CD et al. (1999) Clinical and radiological findings in patients with gas forming renal abscess treated conservatively. J Urol 162: 1273–1276

    Article  CAS  Google Scholar 

  15. Tahir H et al. (2000) Successful medical treatment of acute bilateral emphysematous pyelonephritis. Am J Kidney Dis 36: 1267–1270

    Article  CAS  Google Scholar 

  16. Shokeir AA et al. (1997) Emphysematous pyelonephritis: a 15-year experience with 20 cases. Urology 49: 343–34655

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Mohammed Nayeemuddin.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Nayeemuddin, M., Wiseman, O. & Turner, A. Emphysematous pyelonephritis. Nat Rev Urol 2, 108–112 (2005). https://doi.org/10.1038/ncpuro0095

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpuro0095

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing