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Do statins prevent cancer?

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References

  1. Demierre M-F et al. (2005) Statins and cancer prevention. Nat Rev Cancer 5: 930–942

    Article  CAS  Google Scholar 

  2. Narisawa T et al. (1994) Prevention of 1,2-dimethylhydrazine-induced colon tumorigenesis by HMG-CoA reductase inhibitors, pravastatin and simvastatin, in ICR mice. Carcinogenesis 15: 2045–2048

    Article  CAS  Google Scholar 

  3. Poynter JN et al. (2005) Statins and the risk of colorectal cancer. N Engl J Med 352: 2184–2192

    Article  CAS  Google Scholar 

  4. Hebert PR et al. (1997) Cholesterol lowering with statin drugs, risk of stroke, and total mortality: an overview of randomized trials. JAMA 278: 313–321

    Article  CAS  Google Scholar 

  5. Pfeffer MA et al. (2002) Safety and tolerability of pravastatin in long-term clinical trials: Prospective Pravastatin Pooling (PPP) Project. Circulation 105: 2341–2346

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice.

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Correspondence to Ernest T Hawk.

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Hawk, E., Viner, J. Do statins prevent cancer?. Nat Rev Clin Oncol 3, 478–479 (2006). https://doi.org/10.1038/ncponc0586

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