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References
Motzer RJ et al. (2002) Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 20: 289–296
Rini BI and Small EJ (2005) Biology and clinical development of vascular endothelial growth factor-targeted therapy in renal cell carcinoma. J Clin Oncol 23: 1028–1043
Bukowski RM et al. (2004) Prognostic factors in patients with advanced renal cell carcinoma: development of an international kidney cancer working group. Clin Cancer Res 10: 6310S–6314S
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The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice.
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Glossary
- COX MULTIVARIATE MODEL
-
Statistical regression technique which takes into account the time interval to an outcome in relation to baseline characteristics (of a patient)
- EASTERN COOPERATIVE ONCOLOGY GROUP PERFORMANCE STATUS (ECOG PS)
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A 0 (fully active) to 5 (dead) scoring system to assess the wellbeing of cancer patients and their ability to perform ordinary tasks
- SURVIVAL
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Defined as the time from treatment initiation to the date of death or last follow-up
- VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF)
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A soluble factor that stimulates vascular permeability and blood vessel growth
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Rini, B. What are the prognostic factors for survival in patients with metastatic renal cell carcinoma?. Nat Rev Clin Oncol 2, 292–293 (2005). https://doi.org/10.1038/ncponc0180
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DOI: https://doi.org/10.1038/ncponc0180