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How does antiangiogenic therapy affect brain tumor response to radiation?

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References

  1. Mauceri HJ et al. (1998) Combined effects of angiostatin and ionizing radiation in antitumour therapy. Nature 394: 287–291

    Article  CAS  PubMed  Google Scholar 

  2. Gorski DH et al. (1999) Blockage of the vascular endothelial growth factor stress response increases the antitumor effects of ionizing radiation. Cancer Res 59: 3374–3378

    CAS  PubMed  Google Scholar 

  3. Wachsberger P et al. (2003) Tumor response to ionizing radiation combined with antiangiogenesis or vascular targeting agents: exploring mechanisms of interaction. Clin Cancer Res 9: 1957–1971

    CAS  PubMed  Google Scholar 

  4. Tse V et al. (2003) The temporal-spatial expression of VEGF, angiopoietins-1 and 2, and Tie-2 during tumor angiogenesis and their functional correlation with tumor neovascular architecture. Neurol Res 25: 729–738

    Article  CAS  PubMed  Google Scholar 

  5. Siemeister G et al. (1999) Two independent mechanisms essential for tumor angiogenesis: inhibition of human melanoma xenograft growth by interfering with either the vascular endothelial growth factor receptor pathway or the Tie-2 pathway. Cancer Res 59: 3185–3191

    CAS  PubMed  Google Scholar 

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Acknowledgements

The synopsis was written by Petra Roberts, Associate Editor, Nature Clinical Practice.

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Correspondence to Ralph R Weichselbaum.

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Glossary

VEGFR

Vascular endothelial growth factor receptor; receptor for a soluble factor that stimulates vascular permeability and growth of blood vessels

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Weichselbaum, R. How does antiangiogenic therapy affect brain tumor response to radiation?. Nat Rev Clin Oncol 2, 232–233 (2005). https://doi.org/10.1038/ncponc0177

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