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Is a combination of tramadol and acetaminophen effective for the treatment of acute migraine pain?

Nature Clinical Practice Neurology volume 2, pages 360–361 (2006)Cite this article

boxed-textSilberstein SD et al. (2005) Tramadol/acetaminophen for the treatment of acute migraine pain: findings of a randomized, placebo-controlled trial. Headache 45: 1317–1327

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References

  1. Lipton RB et al. (2002) Efficacy and safety of acetaminophen in the treatment of migraine: results of a randomized, double-blind, placebo-controlled, population-based study. Arch Intern Med 160: 3486–3492

    Article  Google Scholar 

  2. Goldstein J et al. (2005) Acetaminophen, aspirin, and caffeine versus sumatriptan succinate in the early treatment of migraine: results from the ASSET trial. Headache 45: 973–982

    Article  Google Scholar 

  3. Ferrari MD et al. (2001) Oral triptans (serotonin 5-HT1B/1D agonists) in acute migraine treatment: a meta-analysis of 53 trials. Lancet 358: 1668–1675

    Article  CAS  Google Scholar 

  4. Katsarava Z et al. (2001) Clinical features of withdrawal headache following overuse of triptans and other headache drugs. Neurology 57: 1694–1698

    Article  CAS  Google Scholar 

  5. Katsarava Z et al. (2005) Medication overuse headache: rates and predictors for relapse in a 4-year prospective study. Cephalalgia 25: 12–15

    Article  CAS  Google Scholar 

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Acknowledgements

The synopsis was written by Zaza Katsarava and Volker Limmroth.

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Authors and Affiliations

  1. Attending Neurologist in the Department of Neurology at the University Hospital Essen,

    Zaza Katsarava & Volker Limmroth

  2. Associate Professor of Neurology at the University of Essen and Vice Chairman of the Department of Neurology at the University Hospital Essen, Germany

    Zaza Katsarava & Volker Limmroth

Authors
  1. Zaza Katsarava
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  2. Volker Limmroth
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Correspondence to Zaza Katsarava.

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The authors declare no competing financial interests.

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Katsarava, Z., Limmroth, V. Is a combination of tramadol and acetaminophen effective for the treatment of acute migraine pain?. Nat Rev Neurol 2, 360–361 (2006). https://doi.org/10.1038/ncpneuro0223

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