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References
Wanner C et al. (2005) Atorvastatin in patients with type 2 diabetes mellitus undergoing hemodialysis. N Engl J Med 353: 238–248
El-Abbadi M and Giachelli CM (2007) Mechanisms of vascular calcification. Adv Chronic Kidney Dis 14: 54–66
Jin DY et al. (2007) The conversion of vitamin K epoxide to vitamin K quinone and vitamin K quinone to vitamin K hydroquinone uses the same active site cysteines. Biochemistry 46: 7279–7283
Luo G et al. (1997) Spontaneous calcification of arteries and cartilage in mice lacking matrix GLA protein. Nature 386: 78–81
Spronk HM et al. (2001) Matrix Gla protein accumulates at the border of regions of calcification and normal tissue in the media of the arterial vessel wall. Biochem Biophys Res Comm 289: 485–490
Geleijnse JM et al. (2004) Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study. J Nutr 134: 3100–3105
Jie KS et al. (1995) Vitamin K intake and osteocalcin levels in women with and without aortic atherosclerosis: a population-based study. Atherosclerosis 116: 117–123
Booth SL and Suttie JW (1998) Dietary intake and adequacy of vitamin K. J Nutr 128: 785–788
Stein G et al. (1985) Vitamin levels in chronic renal failure and need for supplementation. Blood Purif 3: 52–62
Booth SL et al. (2003) Dietary phylloquinone depletion and repletion in older women. J Nutr 133: 2565–2569
Pilkey RM et al. (2007) Subclinical vitamin K deficiency in hemodialysis patients. Am J Kidney Dis 49: 432–439
Kohlmeier M et al. (1997) Bone health of adult hemodialysis patients is related to vitamin K status. Kidney Int 51: 1218–1221
Miller LM et al. (2006) Cardioprotective medication use in hemodialysis patients. Can J Cardiol 22: 755–760
Koos R et al. (2005) Relation of oral anticoagulation to cardiac valvular and coronary calcium assessed by multislice spiral computed tomography. Am J Cardiol 96: 747–749
Schurgers LJ et al. (2004) Oral anticoagulant treatment: friend or foe in cardiovascular disease? Blood 104: 3231–3232
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Holden, R., Booth, S. Vascular calcification in chronic kidney disease: the role of vitamin K. Nat Rev Nephrol 3, 522–523 (2007). https://doi.org/10.1038/ncpneph0601
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DOI: https://doi.org/10.1038/ncpneph0601
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