Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Is elevated cystatin C a predictor of cardiovascular risk in elderly people without chronic kidney disease?

Nature Clinical Practice Cardiovascular Medicine volume 4, pages 76–77 (2007)Cite this article

boxed-textShlipak MG et al. (2006) Cystatin C and prognosis for cardiovascular and kidney outcomes in elderly persons without chronic kidney disease. Ann Intern Med 145: 237–246

Although the results of the study by Shlipak et al. are very encouraging, it is too early to recommend measurement of cystatin C in routine clinical practice

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

References

  1. Shemesh O et al. (1985) Limitations of creatinine as a filtration marker in glomerulopathic patients. Kidney Int 28: 830–838

    Article  CAS  Google Scholar 

  2. Perkins BA et al. (2005) Detection of renal function decline in patients with diabetes and normal or elevated GFR by serial measurements of serum cystatin C concentrations: results of a 4-year follow-up study. J Am Soc Nephrol 16: 1404–1412

    Article  Google Scholar 

  3. Dharnidharka VR et al. (2002) Serum cystatin C is superior to serum creatinine as a marker of kidney function: a meta-analysis. Am J Kidney Dis 40: 221–226

    Article  CAS  Google Scholar 

  4. Tenstad O et al. (1996) Renal handling of radiolabelled human cystatin C in the rat. Scand J Clin Lab Invest 56: 409–414

    Article  CAS  Google Scholar 

  5. Brosius FC 3rd et al. (2006) Detection of chronic kidney disease in patients with or at increased risk of cardiovascular disease: a science advisory from the American Heart Association Kidney and Cardiovascular Disease Council; the Councils on High Blood Pressure Research, Cardiovascular Disease in the Young, and Epidemiology and Prevention; and the Quality of Care and Outcomes Research Interdisciplinary Working Group: developed in collaboration with the National Kidney Foundation. Circulation 114: 1083–1087

    Article  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Alexandra King, Associate Editor, Nature Clinical Practice.

Author information

Author notes

  1. Department of Internal Medicine II—Cardiology, University of Ulm Medical Center, Robert-Koch Straße 8, D—89081 Ulm, Germany wolfgang.koenig@uniklinik-ulm.de

Authors and Affiliations

  1. W Koenig is a Professor of Medicine/Cardiology, a Consultant in Cardiology, and Head of Clinical Research at the University of Ulm, Germany.,

    Wolfgang Koenig

Authors
  1. Wolfgang Koenig
    View author publications

    You can also search for this author in PubMed Google Scholar

Ethics declarations

Competing interests

The author has received reagents to measure cystatin C from Dade Behring.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Koenig, W. Is elevated cystatin C a predictor of cardiovascular risk in elderly people without chronic kidney disease?. Nat Rev Cardiol 4, 76–77 (2007). https://doi.org/10.1038/ncpcardio0769

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpcardio0769

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing