Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • Practice Point
  • Published:

Is clopidogrel plus aspirin more cost-effective than aspirin alone in high-risk patients with acute coronary syndromes?

This is a preview of subscription content, access via your institution

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

References

  1. Terkelsen CJ et al. (2005) Mortality rates in patients with ST-elevation vs non-ST-elevation acute myocardial infarction: observations from an unselected cohort. Eur Heart J 26: 18–26

    Article  Google Scholar 

  2. Fox KAA et al. (2003) From guidelines to clinical practice: the impact of hospital and geographical characteristics on temporal trends in the management of acute coronary syndromes. The Global Registry of Acute Coronary Events (GRACE). Eur Heart J 24: 1414–1424

    Article  Google Scholar 

  3. The Clopidogrel in Unstable Angina to Prevent Recurrent Events Trial Investigators (2001) Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 345: 494–502

  4. Lindgren P et al. (2004) Cost-effectiveness of clopidogrel in acute coronary syndromes in Sweden: a long-term model based on the CURE trial. J Intern Med 255: 562–570

    Article  CAS  Google Scholar 

  5. The National Institute for Health and Clinical Excellence [http://www.nice.org.uk/page.aspx?o=TA080guidance]

  6. Peters RJG et al. (2003) Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes. Circulation 108: 1682–1687

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The synopsis was written by Chloe Harman, Associate Editor, Nature Clinical Practice.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Keith AA Fox.

Ethics declarations

Competing interests

KAA Fox was co-Chairman and an author of the CURE publication.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fox, K. Is clopidogrel plus aspirin more cost-effective than aspirin alone in high-risk patients with acute coronary syndromes?. Nat Rev Cardiol 2, 444–445 (2005). https://doi.org/10.1038/ncpcardio0297

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1038/ncpcardio0297

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing