Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Structural biology

Toward the ATP synthase mechanism

Nature Chemical Biology volume 6, pages 794–795 (2010)Cite this article

Subjects

ATP synthase synthesizes and hydrolyzes ATP by a unique rotational mechanism. A new study elucidates an important step of the catalytic mechanism, the timing of the release of the reaction product Pi in ATP hydrolysis.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Model of bacterial ATP synthase.

References

  1. Watanabe, R., Iino, R. & Noji, H. Nat. Chem. Biol. 6, 814–820 (2010).

    Article  CAS  Google Scholar 

  2. Nishizaka, T. et al. Nat. Struct. Mol. Biol. 11, 142–148 (2004).

    Article  CAS  Google Scholar 

  3. Shimo-Kon, R. et al. Biophys. J. 98, 1227–1236 (2010).

    Article  CAS  Google Scholar 

  4. Weber, J., Wilke-Mounts, S., Lee, R.S., Grell, E. & Senior, A.E. J. Biol. Chem. 268, 20126–20133 (1993).

    CAS  PubMed  Google Scholar 

  5. Mao, H.Z. & Weber, J. Proc. Natl. Acad. Sci. U.S.A. 104, 18478–18483 (2007).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Joachim Weber is in the Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas, USA, and the Center for Membrane Protein Research, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.,

    Joachim Weber

Authors
  1. Joachim Weber
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Joachim Weber.

Ethics declarations

Competing interests

The author declares no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Weber, J. Toward the ATP synthase mechanism. Nat Chem Biol 6, 794–795 (2010). https://doi.org/10.1038/nchembio.458

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio.458

This article is cited by

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing