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Structural biology

Toward the ATP synthase mechanism

ATP synthase synthesizes and hydrolyzes ATP by a unique rotational mechanism. A new study elucidates an important step of the catalytic mechanism, the timing of the release of the reaction product Pi in ATP hydrolysis.

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Figure 1: Model of bacterial ATP synthase.


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Correspondence to Joachim Weber.

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Weber, J. Toward the ATP synthase mechanism. Nat Chem Biol 6, 794–795 (2010).

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