Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Kinetochore regulation

Let there be light

Nature Chemical Biology volume 13, pages 1058–1059 (2017)Cite this article

Subjects

Kinetochores form the critical interface with spindle microtubules that accounts for chromosome movement and segregation fidelity during mitosis. Spatial and temporal control of motor protein and checkpoint signaling at kinetochores is now possible with a new set of optogenetic tools.

This is a preview of subscription content, access via your institution

Access options

Buy this article

  • Purchase on Springer Link
  • Instant access to full article PDF
Buy now

Prices may be subject to local taxes which are calculated during checkout

Figure 1: Optogenetic control of kinetochore function.

Debbie Maizels/Springer Nature

References

  1. Cheeseman, I.M. Cold Spring Harb. Perspect. Biol. 6, a015826 (2014).

    Article  PubMed Central  Google Scholar 

  2. Maiato, H., Gomes, A.M., Sousa, F. & Barisic, M. Biology (Basel) 6, E13 (2017).

    Google Scholar 

  3. Joglekar, A.P. Biology (Basel) 5, E44 (2016).

    Google Scholar 

  4. Zhang, H. et al. Nat. Chem. Biol. http://dx.doi.org/10.1038/nchembio.2456 (2017).

  5. Deisseroth, K. Nat. Methods 8, 26–29 (2011).

    Article  CAS  Google Scholar 

  6. Ballister, E.R., Aonbangkhen, C., Mayo, A.M., Lampson, M.A. & Chenoweth, D.M. Nat. Commun. 5, 5475 (2014).

    Article  PubMed Central  Google Scholar 

  7. Barisic, M., Aguiar, P., Geley, S. & Maiato, H. Nat. Cell Biol. 16, 1249–1256 (2014).

    Article  CAS  PubMed Central  Google Scholar 

  8. Barisic, M. et al. Science 348, 799–803 (2015).

    Article  CAS  PubMed Central  Google Scholar 

  9. Gudimchuk, N. et al. Nat. Cell Biol. 15, 1079–1088 (2013).

    Article  CAS  PubMed Central  Google Scholar 

  10. Putkey, F.R. et al. Dev. Cell 3, 351–365 (2002).

    Article  CAS  PubMed Central  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Instituto de Biologia Molecular e Celular and Instituto de Investigação e Inovação em Saúde (i3S), Universidade do Porto, Porto, Portugal

    Ana C Figueiredo

  2. Department of Biomedicine, Instituto de Biologia Molecular e Celular and Instituto de Investigação e Inovação em Saúde (i3S), Faculdade de Medicina Universidade do Porto, Porto, Portugal

    Helder Maiato

  3. Whitman Center, Marine Biological Laboratory, Woods Hole, Massachusetts, USA

    Helder Maiato

Authors
  1. Ana C Figueiredo
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Helder Maiato
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Helder Maiato.

Ethics declarations

Competing interests

The authors declare no competing financial interests.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Figueiredo, A., Maiato, H. Let there be light. Nat Chem Biol 13, 1058–1059 (2017). https://doi.org/10.1038/nchembio.2464

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1038/nchembio.2464

Search

Advanced search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing