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Synthetic biology

Sensing with modular receptors

Nature Chemical Biology volume 13, pages 131–132 (2017)Cite this article

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Sensing and responding to diverse extracellular signals is a crucial aspect of cellular decision-making that is currently lacking in the synthetic biology toolkit. The development of modular receptor platforms allows for the rewiring of cellular input–output relationships.

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Figure 1: Comparison of input-output properties for different synthetic receptor platforms in mammalian cells.

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Authors and Affiliations

  1. Jang Hwan Cho and Wilson W. Wong are in the Department of Biomedical Engineering and Biological Design Center, Jamie Brenner, Boston University, Boston, Massachusetts, USA., Boston, USA

    Jamie Brenner, Jang Hwan Cho & Wilson W Wong

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  1. Jamie Brenner
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  2. Jang Hwan Cho
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  3. Wilson W Wong
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Correspondence to Wilson W Wong.

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The authors declare no competing financial interests.

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Brenner, J., Cho, J. & Wong, W. Sensing with modular receptors. Nat Chem Biol 13, 131–132 (2017). https://doi.org/10.1038/nchembio.2290

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