TALE proteins search for target sequences along a DNA substrate in a uniquely one-dimensional and non-rotating fashion.
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J.B. is a part owner of a patent governing the use of TALEs.
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Becker, S., Boch, J. TALEs spin along, but not around. Nat Chem Biol 12, 766–768 (2016). https://doi.org/10.1038/nchembio.2182
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DOI: https://doi.org/10.1038/nchembio.2182