Bacterial translation elongation factor P (EF-P) is essential to overcome ribosome stalling at polyproline stretches during protein synthesis. A new mechanism of EF-P activation, identified in a subset of Bacteria, involves addition of the sugar L-rhamnose to a critical arginine residue.
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Tonetti, M. Translation from sticky to sweet. Nat Chem Biol 11, 243–244 (2015). https://doi.org/10.1038/nchembio.1773
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DOI: https://doi.org/10.1038/nchembio.1773
