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Cytosolic delivery

Just passing through

Intracellular protein delivery has been a major challenge in the field of cell biology for decades. Engineering such delivery is a key step in the development of protein- and antibody-based therapeutics. Now, two different approaches that enable the delivery of antibodies and antibody fragments into the cytosol have been developed.

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Figure 1: Achieving cytosolic protein delivery.

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Correspondence to Ernest Giralt.

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Sánchez-Navarro, M., Teixidó, M. & Giralt, E. Just passing through. Nature Chem 9, 727–728 (2017). https://doi.org/10.1038/nchem.2837

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