Compound 2b

1-Acetyl-3-(2-oxo-2-phenylethylidene)indolin-2-one

From: Construction of bispirooxindoles containing three quaternary stereocentres in a cascade using a single multifunctional organocatalyst

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InChIKey LYEPOPHKDRFMGL-RVDMUPIBSA-N

Synonyms:
  • 1-acetyl-3-(2-oxo-2-phenylethylidene)-1,3-dihydro-2H-indol-2-one

Synthetic procedure: See article for the definitive version of this procedure and for full experimental details.

Compound 2b was synthesized by the general method outlined for compound 2a, changing the Wittig reagent. 1H-NMR (500MHz, CDCl3): δ 8.31 (t, J = 8.0 Hz, 2H), 8.29 (d, J = 8.0 Hz, 2H), 7.87 (d, J = 2.0 Hz, 1H), 7.64 (t, J = 7.5 Hz, 1H), 7.56-7.53 (m, 2H), 7.45-7.42 (m, 1H), 7.20-7.17 (m, 1H), 2.76 (s, 3H). 13C-NMR (125 MHz, CDCl3): δ 190.92, 170.33, 168.26, 142.02, 137.20, 134.69, 134.10, 132.93, 128.99, 128.79, 127.72, 126.79, 125.28, 126.60, 116.54, 26.84. HRMS (ESI) calcd for [M+H] C18H14NO3, m/z: 292.0968, observed:292.0977.

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