Error-free genome segregation depends on the spindle assembly checkpoint (SAC), a signalling network that delays anaphase onset until chromosomes have established proper spindle attachments. Three reports now quantitatively examine the sensitivity and robustness of the SAC response.
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Subramanian, R., Kapoor, T. Slipping past the spindle assembly checkpoint. Nat Cell Biol 15, 1261–1263 (2013). https://doi.org/10.1038/ncb2876
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DOI: https://doi.org/10.1038/ncb2876
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