Primordial germ cell (PGC) development in the human fetus remains relatively uncharted. A new study suggests that epigenetic reprogramming and sex differentiation in human PGCs occur asynchronously over an extended time period. This finding raises questions and implications for in vitro PGC differentiation.
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Laird, D. Humans put their eggs in more than one basket. Nat Cell Biol 15, 13–15 (2013). https://doi.org/10.1038/ncb2665
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DOI: https://doi.org/10.1038/ncb2665
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Erratum: Humans put their eggs in more than one basket
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