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Breaking through an actin cloud

Nature Cell Biology volume 1, pages E197–E198 (1999)Cite this article

Abstract

One of the puzzles about actin-based cellular motility is how directionality is spontaneously imparted in an initially symmetrical situation. A computer model representing actin filaments symmetrically surrounding a bead reproduces the experimentally observed symmetry-breaking and the directed motion of the bead.

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Figure 1: Listeria-like propulsion of ActA-coated beads.

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Authors and Affiliations

  1. the Department of Cell Biology and Anatomy and Lineberger Comprehensive Cancer Center, University of North Carolina-Chapel Hill, Chapel Hill, 27599-7090, North Carolina, USA

    Ken Jacobson

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  1. Ken Jacobson
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Correspondence to Ken Jacobson.

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Jacobson, K. Breaking through an actin cloud . Nat Cell Biol 1, E197–E198 (1999). https://doi.org/10.1038/70225

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