Stem cells, and the microenvironment or 'niche' that influences them, must often reside in a particular location within a tissue to perform their function. Integrin-mediated adhesion is now shown to regulate the location of the stem-cell niche in the Drosophila testis.
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Van Doren, M. Much HUBbub about stem-cell niches. Nat Cell Biol 9, 1344–1345 (2007). https://doi.org/10.1038/ncb1207-1344
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DOI: https://doi.org/10.1038/ncb1207-1344