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Ring around the genes

Nature Cell Biology volume 9, pages 1343–1344 (2007)Cite this article

How is RNA Polymerase II (RNAP) regulated at poised loci in embryonic stem cells? Recent work provides new insights into Ring1-mediated transcriptional control of this important subset of developmental regulatory genes.

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Figure 1: Many developmental genes in mammalian embryonic stem cells have a special bivalent histone-modification pattern that includes the activation-associated H3K4me3 and the repression-associated H3K27me3.

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Authors and Affiliations

  1. Tanya M. Specktor and Judd C. Rice are in the Department of Biochemistry and Molecular Biology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA. juddrice@usc.edu,

    Tanya M. Spektor & Judd C. Rice

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  1. Tanya M. Spektor
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  2. Judd C. Rice
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Spektor, T., Rice, J. Ring around the genes. Nat Cell Biol 9, 1343–1344 (2007). https://doi.org/10.1038/ncb1207-1343

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