Abstract
Here we show that the rate of poleward chromosome motion in zw10-null mutants is greatly attenuated throughout the division process, and that chromosome disjunction at anaphase is highly asynchronous. Our results show that ZW10 protein, together with Rod, is involved in production and/or regulation of the force reponsible for poleward chromosome motion.
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Acknowledgements
We thank B. C. Williams, R. Cole, H. Chotowski, R. Glaser and A. Khodjakov for assistance. This work was supported by NIH GMS grants 40198 (to C.L.R.) and 48430 (to M.L.G.).
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Savoian, M., Goldberg, M. & Rieder, C. The rate of poleward chromosome motion is attenuated in Drosophila zw10 and rod mutants. Nat Cell Biol 2, 948–952 (2000). https://doi.org/10.1038/35046605
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DOI: https://doi.org/10.1038/35046605
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