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A bacterial virulence factor that dissipates tension

Nature Cell Biology volume 11, pages 1174–1175 (2009)Cite this article

Various microbes harness the actin polymerization machinery through their surface proteins to allow intracellular motility within host cells, but other virulence factors regulate dissemination. The cortical actin tension of polarized cells may represent a physical barrier that hinders the formation of microbial protrusions during cell-to-cell spreading.

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Figure 1: Two ways to hijack cell junctions to promote bacterial dissemination.

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Authors and Affiliations

  1. Stéphane Romero and Guy Tran Van Nhieu are in the department of Biology, College de France, Inserm U971, Paris, France. guy.tran-van-nhieu@college-de-france.fr,

    Stéphane Romero & Guy Tran Van Nhieu

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  1. Stéphane Romero
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  2. Guy Tran Van Nhieu
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Romero, S., Van Nhieu, G. A bacterial virulence factor that dissipates tension. Nat Cell Biol 11, 1174–1175 (2009). https://doi.org/10.1038/ncb1009-1174

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