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Stressed out? Make some modifications!

Nature Cell Biology volume 10, pages 1129–1130 (2008)Cite this article

Stress granules and processing bodies are related mRNA-containing granules implicated in controlling mRNA translation and decay. A genomic screen identifies numerous factors affecting granule formation, including proteins involved in O-GlcNAc modifications. These results highlight the importance of post-translational modifications in translational control and mRNP granule formation.

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Figure 1: A model of the possible mRNA transitions among the translating pool, P-bodies (pink) and stress granules (green).

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Authors and Affiliations

  1. Angela Hilliker and Roy Parker are in the Department of Molecular and Cellular Biology and Howard Hughes Medical Institute, University of Arizona, Tucson, AZ, 85721-0106, USA. rrparker@u.arizona.edu,

    Angela Hilliker & Roy Parker

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  1. Angela Hilliker
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  2. Roy Parker
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Hilliker, A., Parker, R. Stressed out? Make some modifications!. Nat Cell Biol 10, 1129–1130 (2008). https://doi.org/10.1038/ncb1008-1129

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