Rises in cytoplasmic Ca2+ concentration control a diverse array of key cellular functions. One ubiquitous route for raising Ca2+ concentration is through store-operated calcium channels in the plasma membrane. However, the molecular basis of store-operated entry has remained a mystery. Now, exciting new research may have identified the molecular composition of a store-operated channel.
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Parekh, A. A CRAC current tango. Nat Cell Biol 8, 655–656 (2006). https://doi.org/10.1038/ncb0706-655
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DOI: https://doi.org/10.1038/ncb0706-655
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