Chordate claudins are core components of tight junctions. By contrast, VAB-9, a nematode four-pass transmembrane protein related to claudins, localizes to adherens junctions and contributes to cell adhesion and actin–plasma membrane association.
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Tepass, U. Claudin complexities at the apical junctional complex. Nat Cell Biol 5, 595–597 (2003). https://doi.org/10.1038/ncb0703-595
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DOI: https://doi.org/10.1038/ncb0703-595
