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Anchoring microtubules at the spindle poles

In the cell, microtubule organizing centers (MTOCs) dynamically nucleate microtubules and arrange them in functional patterns, but microtubule anchoring to MTOCs is not well understood. A novel fission-yeast protein that anchors the γ-tubulin-containing nucleating complex (γ-TuC) at the spindle pole during mitosis has now been described. The work highlights the complex regulation of microtubule anchoring.

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Figure 1: The fission yeast protein msd1p functions in microtubule anchoring.

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Paoletti, A., T., P. Anchoring microtubules at the spindle poles. Nat Cell Biol 9, 619–621 (2007). https://doi.org/10.1038/ncb0607-619

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