A recent study has shown that the Ssl1 subunit of the general transcription/DNA repair factor TFIIH contains ubiquitin ligase activity that is dependent on a RING domain. The RING domain is required for transcription of a subset of yeast genes that are involved in DNA damage repair, thus uncovering a novel ubiquitination-associated function for TFIIH in the repair process.
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Osley, M. Transcription RINGs in repair. Nat Cell Biol 7, 553–555 (2005). https://doi.org/10.1038/ncb0605-553
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DOI: https://doi.org/10.1038/ncb0605-553
