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The cutting edge of mitochondrial fusion

Mitochondrial membrane fusion contributes to the shape and distribution of mitochondria in the eukaryotic cytoplasm. Recent work shows that a key component of the fusion reaction, Mgm1p, is activated by a novel mitochondrial protease related to the Drosophila melanogaster signalling protein Rhomboid.

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Figure 1: Alterations of mitochondrial morphology during growth of S. cerevisiae.

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Yaffe, M. The cutting edge of mitochondrial fusion. Nat Cell Biol 5, 497–499 (2003). https://doi.org/10.1038/ncb0603-497b

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