Mitochondrial membrane fusion contributes to the shape and distribution of mitochondria in the eukaryotic cytoplasm. Recent work shows that a key component of the fusion reaction, Mgm1p, is activated by a novel mitochondrial protease related to the Drosophila melanogaster signalling protein Rhomboid.
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Ratiometric high-resolution imaging of JC-1 fluorescence reveals the subcellular heterogeneity of astrocytic mitochondria
Pflügers Archiv - European Journal of Physiology Open Access 01 September 2011
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References
Yaffe, M.P. Science 283, 1493–1497 (1999).
Yaffe, M.P. Nat. Cell Biol. 1, E149–E150 (1999).
Frank, S. et al. Dev. Cell 1, 515–525 (2001).
McQuibban, G.A., Saurya, S. & Freeman, M. Nature DOI: 10.1038/nature01633 (2003).
Herlan, M., Vogel, F., Bornhovd, C., Neupert, W. & Reichert, A.S. J. Biol. Chem. DOI: 10.1074/jbc.M211311200 (2003).
Sesaki, H. & Jensen, R.E. J. Cell Biol. 147, 699–706 (1999).
Shaw, J.M. & Nunnari, J. Trends Cell Biol. 12, 178–184 (2002).
Sesaki, H., Southard, S.M., Yaffe, M.P. & Jensen, R.E. Mol. Biol. Cell (in the press).
Wong, E.D. et al. J. Cell Biol. 160, 303–311 (2003).
Sturtevant, M.A., Roark, M. & Bier, E. Genes Dev. 7, 961–973 (1993).
Schweitzer, R. & Shilo, B.Z. Trends Genet. 13, 191–196 (1997).
Rutledge, B.J., Zhang, K., Bier, E., Jan, Y.N. & Perrimon, N. Genes Dev. 6, 1503–1517 (1992).
Lee, J.R., Urban, S., Garvey, C.F. & Freeman, M. Cell 107, 161–171 (2001).
Dimmer, K.S. et al. Mol. Biol. Cell 13, 847–853 (2002).
Esser, K., Tursun, B., Ingenhoven, M., Michaelis, G. & Pratje, E. J. Mol. Biol. 323, 835–843 (2002).
Shepard, K.A. & Yaffe, M.P. J. Cell Biol. 144, 711–720 (1999).
Fekkes, P., Shepard, K.A. & Yaffe, M.P. J. Cell Biol. 151, 333–340 (2000).
Delettre, C. et al. Nature Genet. 26, 207–210 (2000).
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Yaffe, M. The cutting edge of mitochondrial fusion. Nat Cell Biol 5, 497–499 (2003). https://doi.org/10.1038/ncb0603-497b
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DOI: https://doi.org/10.1038/ncb0603-497b
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