Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

  • News & Views
  • Published:

Caveolae on the move

Caveolae deliver simian virus 40 (SV40) to a new compartment called a caveosome, where the virus is sorted for transport to the smooth endoplasmic reticulum (ER). This pathway bypasses other endocytic organelles, and early steps may be shared by lipid rafts and certain glycosylphosphatidylinositol (GPI)-linked proteins.

This is a preview of subscription content, access via your institution

Relevant articles

Open Access articles citing this article.

Access options

Buy this article

Prices may be subject to local taxes which are calculated during checkout

Figure 1: SV40 enters cells by binding to receptors and subsequent capture by caveolae.

References

  1. Anderson, R. G. W. Ann. Rev. Biochem. 67, 199–225 (1998).

    Article  CAS  Google Scholar 

  2. Kurzchalia, T. V. & Parton, R. G. Curr. Opin. Cell Biol. 11, 424–431 ( 1999).

    Article  CAS  Google Scholar 

  3. Brown, D. A. & London, E. J. Biol. Chem. 275, 17221–17224 (2000).

    Article  CAS  Google Scholar 

  4. van Meer, G. J. Cell Biol. 152, F29–F34 (2001).

    Article  CAS  Google Scholar 

  5. Pelkmans, L., Kartenbeck, J. & Helenius, A. Nature Cell Biol. 3, 473– 483 (2001).

    Article  CAS  Google Scholar 

  6. Nichols, B. J. et al. J. Cell Biol. 153 (in the press).

  7. Kartenbeck, J., Stukenbrok, H. & Helenius, A. J. Cell Biol. 109, 2721– 2729 (1989).

    Article  CAS  Google Scholar 

  8. Anderson, H. A., Chen, Y. & Norkin, L. C. Mol. Biol. Cell 7, 1825– 1834 (1996).

    Article  CAS  Google Scholar 

  9. Stang, E., Kartenbeck, J., & Parton, R. G. Mol. Biol. Cell 8, 47– 57 (1997).

    Article  CAS  Google Scholar 

  10. Mayor, S., Sabharanjak, S. & Maxfield, F. R. EMBO J. 17, 4626– 4638 (1998).

    Article  CAS  Google Scholar 

  11. Pol, A. et al. J. Cell Biol. 152, 1057– 1070 (2001).

    Article  CAS  Google Scholar 

  12. Ostermeyer, A. G. et al. J. Cell Biol. 152, 1071– 1078 (2001).

    Article  CAS  Google Scholar 

  13. Fujimoto, T., Kogo, H., Ishiguro, K. & Tauchi, K, Nomura, R. J. Cell Biol. 152, 1079– 1086 (2001).

    Article  CAS  Google Scholar 

  14. Parton, R. G., Joggerst, B. & Simons, K. J. Cell Biol. 127, 1199– 1215 (1994).

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Rights and permissions

Reprints and permissions

About this article

Cite this article

Pfeffer, S. Caveolae on the move. Nat Cell Biol 3, E108–E109 (2001). https://doi.org/10.1038/35074625

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1038/35074625

This article is cited by

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing