The assembly of actin networks is dependent on nucleation-promoting factors. A new study identifies JMY as a protein containing two separate nucleation-promoting activities that shuttles between the nucleus and the cytoplasm and promotes cell migration. These observations indicate that JMY is an important factor controlling actin dynamics in motile cells.
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References
Chesarone, M. A. & Goode, B. L. Curr. Opin. Cell Biol. 21 (1), 28–37 (2009).
Campellone, K. G., Webb, N. J., Znameroski, E. A. & Welch, M. D. Cell 134, 148–161 (2008).
Linardopoulou, E. V. et al. PLoS Genet. 3, e237 (2007).
Quinlan, M. E., Heuser, J. E., Kerkhoff, E. & Mullins, R. D. Nature 433, 382–388 (2005).
Zuchero, J. B., Coutts, A. S., Quinlan, M. E., La Thangue, N. B. & Mullins, R. D. Nature Cell Biol. 11, 451–459 (2009).
Shikama, N. et al. Mol. Cell 4, 365–376 (1999).
Vartiainen, M. K. FEBS Lett. 582, 2033–2040 (2008).
Coutts, A. S., Boulahbel, H., Graham, A. & La Thangue, N. B. EMBO Rep. 8, 84–90 (2007).
Perez-Moreno, M. & Fuchs, E. Dev. Cell 11, 601–612 (2006).
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Roadcap, D., Bear, J. Double JMY: making actin fast. Nat Cell Biol 11, 375–376 (2009). https://doi.org/10.1038/ncb0409-375
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DOI: https://doi.org/10.1038/ncb0409-375