The remarkable fidelity of chromosome segregation during mitosis and meiosis is critical for preventing birth defects and diseases. The Aurora protein kinases prevent defects in segregation by correcting mistakes in chromosome attachment to the spindle before cells divide.
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References
Lampson, M.A., Renduchitala, K., Khodjakov, A. & Kapoor, T.M. Nature Cell Biol. 6, 232–237 (2004).
Rieder, C.L. & Salmon, E.D. Trends Cell Biol. 8, 310–318 (1998).
Mitchison, T. & Kirschner, M. Nature 312, 237–242 (1984).
Lew, D.J. & Burke, D.J. Annu. Rev. Genet. 37, 251–282 (2003).
Carmena, M. & Earnshaw, W.C. Nature Rev. Mol. Cell Biol. 4, 842–854 (2003).
Tanaka, T.U. et al. Cell 108, 317–329 (2002).
Dewar, H., Tanaka, K., Naysmith, K. & Tanaka, T.U. Nature DOI:10.1038/nature02328 (2004).
Pinsky, B.A., Tatsutani, S.Y., Collins, K.A. & Biggins, S. Dev. Cell 5, 735–745 (2003).
Biggins, S. & Murray, A.W. Genes Dev. 15, 3118–3129 (2001).
Ditchfield, C. et al. J. Cell Biol. 161, 267–280 (2003).
Hauf, S. et al. J. Cell Biol. 161, 281–294 (2003).
Nicklas, R.B. & Koch, C.A. J. Cell Biol. 43, 40–50 (1969).
Desai, A., Verma, S., Mitchison, T.J. & Walczak, C.E. Cell 96, 69–78 (1999).
Andrews, P.D. et al. Dev. Cell 6, 253–268 (2004).
Lan, W. et al. Curr. Biol. (in the press).
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Biggins, S. Correcting SYNful attachments. Nat Cell Biol 6, 181–183 (2004). https://doi.org/10.1038/ncb0304-181
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DOI: https://doi.org/10.1038/ncb0304-181