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Heads or tails: can Wnt tell which one is up?

Nature Cell Biology volume 10, pages 122–124 (2008)Cite this article

Planarian flatworms regenerate their heads and tails after amputation. It turns out that they use Wnt–β-catenin signalling to determine where the head and the tail should form.

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Figure 1: Wnt–β-catenin signalling regulates head and tail formation during planarian regeneration and vertebrate embryogenesis.

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Authors and Affiliations

  1. Elly M. Tanaka is at the Max Planck Institute for Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, D-01307 Dresden, Germany and the Center for Regenerative Therapies, Dresden. Gilbert Weidinger is at the Biotechnology Center of the Technical University Dresden, Tatzberg 47, D-01307 Dresden, Germany. tanaka@mpi-cbg.de gilbert.weidinger@biotec.tu-dresden.de,

    Elly M. Tanaka & Gilbert Weidinger

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  1. Elly M. Tanaka
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  2. Gilbert Weidinger
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Tanaka, E., Weidinger, G. Heads or tails: can Wnt tell which one is up?. Nat Cell Biol 10, 122–124 (2008). https://doi.org/10.1038/ncb0208-122

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