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Facing up to Mena: Tes(ting) times for EVH1 domains

Nature Cell Biology volume 10, pages 118120 (2008) | Download Citation

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Ena/VASP family members have a common binding interface on their EVH1 domains for FPPPP motifs in partner proteins. The finding that Tes, a protein lacking FPPPP motifs, competes specifically for the FPPPP ligand site on Mena, provides new insights into the differential regulation of Ena/VASP proteins.

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Affiliations

  1. J. Victor Small is at the Austrian Academy of Sciences, IMBA - Institute of Molecular Biotechnology, Dr. Bohr-Gasse 3, 1030 Vienna, Vienna, A-1030, Austria.  vic.small@imba.oeaw.ac.at

    • J. Victor Small

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DOI

https://doi.org/10.1038/ncb0208-118

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