Specific gene expression patterns must be tightly regulated for eukaryotic cells to acquire unique structural and functional features. A key step is transcriptional initiation, during which epigenetic activators are thought to facilitate the process by establishing and maintaining transcription-competent chromatin structures. Accumulating evidence shows that an epigenetic regulator can also control the next step — transcriptional elongation.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$209.00 per year
only $17.42 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
References
Turner, B.M. Cell 111, 285–291 (2002).
Breiling, A. & Orlando, V. Nature Struct. Biol. 9, 894–896 (2002).
Smith, S.T. et al. Nature Cell Biol. 6, 162–167 (2004).
Sims, R.J., Nishioka, K. & Reinberg, D. Trends Genet. 19, 629–639 (2003).
Hampsey, M. & Reinberg, D. Cell 113, 429–432 (2003).
Saunders, A. et al. Science 301, 1094–1096 (2003).
Andrulis, E.D., Guzman, E., Doring, P., Werner, J. & Lis, J.T. Genes Dev. 14, 2635–2649 (2000).
Rougvie, A.E. & Lis, J.T. Cell 54, 795–804 (1988).
Petruk, S. et al. Science 294, 1331–1334 (2001).
Nislow, C., Ray, E. & Pillus, L. Mol. Biol. Cell 8, 2421–2436 (1997).
Schneider, R., Bannister, A.J. & Kouzarides, T. Trends Biochem. Sci. 27, 396–402 (2002).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Sanchez-Elsner, T., Sauer, F. The heat is on with TAC1. Nat Cell Biol 6, 92–93 (2004). https://doi.org/10.1038/ncb0204-92
Issue Date:
DOI: https://doi.org/10.1038/ncb0204-92