Integrins are cell surface receptors for extracellular matrix proteins and, as such, regulate adhesive cell–matrix interactions. New findings indicate that the β4 integrin subunit can also function as a signalling effector for the activated receptor tyrosine kinase Met and enhance invasive growth independent of its adhesive role.
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Klein, R. Novel effector function for an old receptor. Nat Cell Biol 4, E11–E12 (2002). https://doi.org/10.1038/ncb0102-e11
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DOI: https://doi.org/10.1038/ncb0102-e11
