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Getting in shape with Rho

Nature Cell Biology volume 2, pages E7–E9 (2000)Cite this article

Abstract

The Rho GTPases are potent regulators of the actin cytoskeleton and consequently influence many aspects of cell shape and movement. In vivo, Rho activity appears to be a critical determinant of tissue morphogenesis during several stages of embryonic development.

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Figure 1: In Drosophila development, the Rho GTPase mediates signalling pathways that direct several distinct morphogenetic processes.

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Authors and Affiliations

  1. the Department of Medicine, Harvard Medical School, and the Cancer Center of Massachusetts General Hospital, Building 149, 13th Street, Charlestown, 02129, Massachusetts, USA

    Jeffrey Settleman

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  1. Jeffrey Settleman
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Settleman, J. Getting in shape with Rho. Nat Cell Biol 2, E7–E9 (2000). https://doi.org/10.1038/71390

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