The genome sequence of an engineered Clostridium strain will likely facilitate the development of bacterial cancer therapies.
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References
Bettegowda, C. et al. Nat. Biotechnol. 24, 1573–1580 (2006).
Dang, L.H., Bettegowda, C., Huso, D.L., Kinzler, K.W. & Vogelstein, B. Proc. Natl. Acad. Sci. USA 98, 15155–15160 (2001).
Jain, R.K. & Forbes, N.S. Proc. Natl. Acad. Sci. USA 98, 14748–14750 (2001).
Brown, J.M. & Giaccia, A.J. Cancer Res. 58, 1408–1416 (1998).
Theys, J. et al. Appl. Environ. Microbiol. 65, 4295–4300 (1999).
Zhao, M. et al. Proc. Natl. Acad. Sci. USA 102, 755–760 (2005).
Low, K.B. et al. Nat. Biotechnol. 17, 37–41 (1999).
Pawelek, J.M., Low, K.B. & Bermudes, D. Cancer Res. 57, 4537–4544 (1997).
Fujimori, M., Amano, J. & Taniguchi, S. Curr. Opin. Drug Discov. Devel. 5, 200–203 (2002).
Yu, Y.A. et al. Nat. Biotechnol. 22, 313–320 (2004).
Liu, H. et al. J. Bacteriol. 186, 164–178 (2004).
Lambin, P. et al. Anaerobe 4, 183–188 (1998).
Kasinskas, R.W. & Forbes, N.S. Biotechnol. Bioeng. 94, 710–721 (2006).
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Forbes, N. Profile of a bacterial tumor killer. Nat Biotechnol 24, 1484–1485 (2006). https://doi.org/10.1038/nbt1206-1484
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DOI: https://doi.org/10.1038/nbt1206-1484
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