Skip to main content

Thank you for visiting nature.com. You are using a browser version with limited support for CSS. To obtain the best experience, we recommend you use a more up to date browser (or turn off compatibility mode in Internet Explorer). In the meantime, to ensure continued support, we are displaying the site without styles and JavaScript.

A systems view of host defense

Large-scale perturbations unravel the complex networks of activated dendritic cells.

Access options

Rent or Buy article

Get time limited or full article access on ReadCube.

from$8.99

All prices are NET prices.

Figure 1: Toll-like receptor (TLR)-activated gene regulatory networks.

Kim Caesar

References

  1. 1

    Ishii, K.J., Koyama, S., Nakagawa, A., Coban, C. & Akira S. Cell Host Microbe 3, 352–63 (2008).

    CAS  Article  Google Scholar 

  2. 2

    Ramsey, S.A., et al. PLoS Comput. Biol. 4, e1000021 (2008).

    Article  Google Scholar 

  3. 3

    Amit, I., et al. Science 326, 257–263 (2009).

    CAS  Article  Google Scholar 

  4. 4

    Gilchrist, M., et al. Nature 441, 173–178 (2006).

    CAS  Article  Google Scholar 

  5. 5

    Litvak, V. et al. Nat. Immunol. 10, 437–443 (2009).

    CAS  Article  Google Scholar 

  6. 6

    Nilsson, R. et al. Genomics 88, 133–142 (2006).

    CAS  Article  Google Scholar 

  7. 7

    Suzuki, H. et al. Nat. Genet. 41, 553–562 (2009).

    CAS  Article  Google Scholar 

  8. 8

    Beutler, B. et al. Annu. Rev. Immunol. 24, 353–389 (2006).

    CAS  Article  Google Scholar 

  9. 9

    Shendure, J. & Ji, H. Nat. Biotechnol. 26, 1135–1145 (2008).

    CAS  Article  Google Scholar 

  10. 10

    Meyer, M., Stenzel, U. & Hofreiter, M. Nat. Protoc. 3, 267–278 (2008).

    CAS  Article  Google Scholar 

Download references

Author information

Affiliations

Authors

Corresponding author

Correspondence to Daniel E Zak.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Zak, D., Aderem, A. A systems view of host defense. Nat Biotechnol 27, 999–1001 (2009). https://doi.org/10.1038/nbt1109-999

Download citation

Further reading

Search

Quick links

Nature Briefing

Sign up for the Nature Briefing newsletter — what matters in science, free to your inbox daily.

Get the most important science stories of the day, free in your inbox. Sign up for Nature Briefing