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Induced pluripotency and cellular alchemy

Nature Biotechnology volume 24, pages 1363–1364 (2006)Cite this article

Fibroblasts have been transmuted into pluripotent cells by the introduction of four factors.

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Figure 1: Simplified schematic showing induced pluripotent stem (iPS) and other cells prescriptively (de)differentiated in vitro and their relationships to in vivo differentiation.

Katie Ris

References

  1. Takahashi, K. & Yamanaka, S. Cell 126, 663–676 (2006).

    Article  CAS  Google Scholar 

  2. Niwa, H., Miyazaki, J. & Smith, A.G. Nat. Genet. 24, 372–376 (2000).

    Article  CAS  Google Scholar 

  3. Loh, Y.H. et al. Nat. Genet. 38, 431–440 (2006).

    Article  CAS  Google Scholar 

  4. Li, Y. et al. Blood 105, 635–637 (2005).

    Article  CAS  Google Scholar 

  5. Nakatake, Y. et al. Mol. Cell Biol., 26, 7772–7782 (2006).

    Article  CAS  Google Scholar 

  6. Cartwright, P. et al. Development 132, 885–896 (2005).

    Article  CAS  Google Scholar 

  7. Monk, M. & Holding, C. Oncogene 20, 8085–8091 (2001).

    Article  CAS  Google Scholar 

  8. Adhikary, S. & Eilers, M. Nat. Rev. Mol. Cell Biol. 6, 635–645 (2005).

    Article  CAS  Google Scholar 

  9. Rowland, B.D. & Peeper, D.S. Nat. Rev. Cancer 6, 11–23 (2006).

    Article  CAS  Google Scholar 

  10. Tsukamoto, T. et al. Histopathology 46, 649–658 (2005).

    Article  CAS  Google Scholar 

  11. Silva, J., Chambers, I., Pollard, S. & Smith, A. Nature 441, 997–1001 (2006).

    Article  CAS  Google Scholar 

  12. Tokuzawa, Y. et al. Mol. Cell. Biol. 23, 2699–2708 (2003).

    Article  CAS  Google Scholar 

  13. Li, J., Ishii, T., Wen, D. & Mombaerts, P. Curr. Biol. 15, R756–R757 (2005).

    Article  CAS  Google Scholar 

  14. Hübner, K. et al. Science 300, 1251–1256 (2003).

    Article  Google Scholar 

  15. Nayernia, K. et al. Dev. Cell 11, 125–132 (2006).

    Article  CAS  Google Scholar 

Download references

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  1. Laboratory of Mammalian Molecular Embryology, RIKEN Center for Developmental Biology, 2-2-3 Minatojima Minamimachi, Chuo-ku, 650-0047, Kobe, Japan

    Anthony C F Perry

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  1. Anthony C F Perry
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Perry, A. Induced pluripotency and cellular alchemy. Nat Biotechnol 24, 1363–1364 (2006). https://doi.org/10.1038/nbt1106-1363

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