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Protein hinges for bioelectronics

Changes in protein conformation have been exploited to create chemoresponsive bioelectronic sensors.

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Figure 1: Allosterically controlled electrochemical transduction of the binding of maltose to the maltose-binding protein by the “hinging” mechanism.

© Bob Crimi

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Willner, I. Protein hinges for bioelectronics. Nat Biotechnol 19, 1023–1024 (2001). https://doi.org/10.1038/nbt1101-1023

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