Yeast has been engineered so that the binding of small-molecule ligands to a target protein can be simply detected by changes in growth.
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Insertional protein engineering for analytical molecular sensing
Microbial Cell Factories Open Access 03 April 2006
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Vidan, S., Snyder, M. Making drug addicts out of yeast. Nat Biotechnol 19, 1022–1023 (2001). https://doi.org/10.1038/nbt1101-1022
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DOI: https://doi.org/10.1038/nbt1101-1022
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Insertional protein engineering for analytical molecular sensing
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